DSIP

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide that modulates the stress response and enhances deep sleep, specifically the delta wave sleep stage (slow wave sleep), which is the most restorative phase of the sleep cycle. It was originally discovered in 1977 when researchers isolated it from the brains of animals during induced sleep states, finding a peptide that appeared to trigger deep sleep when administered. DSIP works by regulating cortisol levels, reducing stress, and promoting the deep, restorative sleep stages critical for physical recovery, immune function, cognitive performance, and hormonal balance. Unlike sedatives that force sleep through CNS depression, DSIP works by normalizing the body’s natural sleep-wake cycles and stress response making it particularly valuable for individuals with chronic stress, insomnia, or disrupted circadian rhythms. In short: DSIP is the stress regulation and deep sleep peptide that lowers cortisol, enhances slow-wave sleep, and supports the body’s natural recovery processes.